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Tag mutation [678 articles]

Recent papers classified by the tag mutation.
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  • Epistasis between deleterious mutations and the evolution of recombination
    Trends in Ecology & Evolution, Vol. In Press, Corrected Proof
    by Roger D Kouyos, Olin K Silander, Sebastian Bonhoeffer
    posted to evolution mutation by zwang on 2007-03-19 09:45:41 as ** along with 3 people and 2 groups pradiptaray dchughes xingxu G4ID Genetics-of-Gambling
  • Morphological evolution through multiple cis-regulatory mutations at a single gene
    Nature (15 July 2007)
    by Alistair P Mcgregor, Virginie Orgogozo, Isabelle Delon, Jennifer Zanet, Dayalan G Srinivasan, François Payre, David L Stern
    posted to evolution morphological mutation regulatory by zwang on 2007-08-09 15:32:07 as ** along with 7 people and 2 groups carlfulp dpollard djkt Stew xingxu cisevol emptyhb EisenLab cis-regulatory-evolution
  • Transmission of Influenza Virus in a Mammalian Host Is Increased by PB2 Amino Acids 627K or 627E/701N
    PLoS Pathog, Vol. 5, No. 1. (2 January 2009), e1000252.
    by John Steel, Anice C Lowen, Samira Mubareka, Peter Palese
    posted to virus polymerase mutation influenza by zwang on 2009-01-05 08:41:31 as *** along with 1 person mrphospho
  • The Ascent of the Abundant: How Mutational Networks Constrain Evolution
    PLoS Comput Biol, Vol. 4, No. 7. (18 July 2008), e1000110.
    by Matthew C Cowperthwaite, Evan P Economo, William R Harcombe, Eric L Miller, Lauren A Meyers
    posted to evolution modeling mutation network rna by zwang on 2008-07-22 06:59:06 as ** along with 6 people Ema djkt friendpine biomcgary provero shoshin
  • Toward a Comprehensive Temperature-Sensitive Mutant Repository of the Essential Genes of Saccharomyces cerevisiae
    Molecular Cell, Vol. 30, No. 2. (25 April 2008), pp. 248-258.
    by Shay Ben-Aroya, Candice Coombes, Teresa Kwok, Kathryn A O'Donnell, Jef D Boeke, Philip Hieter
    posted to gene mutation yeast by zwang on 2008-06-02 07:17:18 as ****
  • Escherichia coli RNase P RNA: Substrate Ribose Modifications at G+1, but Not Nucleotide - 1/+73 Base Pairing, Affect the Transition State for Cleavage Chemistry
    Journal of Molecular Biology, Vol. In Press, Corrected Proof
    by Simona Cuzic, Karin A Heidemann, Jens Wöhnert, Roland K Hartmann
    posted to ecoli mutation rna rnasep by zwang on 2008-05-05 14:16:50 as ****
  • Non-random coextinctions in phylogenetically structured mutualistic networks
    Nature, Vol. 448, No. 7156., pp. 925-928.
    by Enrico L Rezende, Jessica E Lavabre, Paulo R Guimarães, Pedro Jordano, Jordi Bascompte
    posted to co-extinction mutation network phylogeny by zwang on 2007-08-28 04:03:13 as *** along with 1 person cmm
  • Adaptive Mutations in Bacteria: High Rate and Small Effects
    Science, Vol. 317, No. 5839. (10 August 2007), pp. 813-815.
    by Lilia Perfeito, Lisete Fernandes, Catarina Mota, Isabel Gordo
    posted to bacterial genome mutation by zwang on 2007-08-15 03:22:01 as * along with 3 people and 1 group alexeid stevanspringer operon FAB-lab
  • High-precision mapping of protein protein interfaces: an integrated genetic strategy combining en masse mutagenesis and DNA-level parallel analysis on a yeast two-hybrid platform.
    Nucleic Acids Res (15 August 2007)
    by Maria Pajunen, Hilkka Turakainen, Eini Poussu, Johan Peränen, Mauno Vihinen, Harri Savilahti
    posted to interaction interface mutation protein yeast by zwang on 2007-09-17 09:52:27 as ***** along with 2 people Terkko yeastyboy
  • Analysis of a point mutation in H5N1 avian influenza virus hemagglutinin in relation to virus entry into live mammalian cells
    Archives of Virology
    by Yan Su, Huai-Yi Yang, Bao-Jiang Zhang, Hong-Ling Jia, Po Tien
    posted to mutation influenza hemagglutinin avian by zwang on 2008-12-19 08:16:45 as ***
  • Crystal Structure of an Ancient Protein: Evolution by Conformational Epistasis
    Science (16 August 2007), 1142819.
    by Eric A Ortlund, Jamie T Bridgham, Matthew R Redinbo, Joseph W Thornton
    posted to co-evolution epistasis evolution mutation protein structure by zwang on 2007-08-18 08:37:30 as *** along with 4 people and 1 group bicko dpollard csjonline ramensky EisenLab
  • Understanding the Evolutionary Fate of Finite Populations: The Dynamics of Mutational Effects
    PLoS Biology, Vol. 5, No. 4. (1 April 2007), e94.
    by Olin K Silander, Olivier Tenaillon, Lin Chao
    posted to dynamics evolution mutation by zwang on 2007-04-19 15:16:28 as * along with 3 people and 1 group stevanspringer joepickrell yvoronin FAB-lab
  • Use of RNase P for efficient preparation of yeast tRNATyr transcript and its mutants.
    J Biochem (Tokyo), Vol. 139, No. 1. (January 2006), pp. 123-127.
    by J Fukunaga, M Gouda, K Umeda, S Ohno, T Yokogawa, K Nishikawa
    posted to mutation rnasep trna yeast by zwang on 2007-07-26 08:28:06 as ***
  • Phenotypic Mutation Rates and the Abundance of Abnormal Proteins in Yeast
    PLoS Computational Biology, Vol. 3, No. 11. (1 November 2007), e203.
    by Martin Willensdorfer, Reinhard Bürger, Martin A Nowak
    posted to mutation phenotype protein yeast by zwang on 2007-12-10 04:21:57 as ** along with 2 people Ema bpcusack
  • Which evolutionary processes influence natural genetic variation for phenotypic traits?
    Nat Rev Genet, Vol. 8, No. 11. (November 2007), pp. 845-856.
    by Thomas Mitchell-Olds, John H Willis, David B Goldstein
    posted to evolution genetic mutation phenotype by zwang on 2007-10-22 01:53:23 as *** along with 3 people and 2 groups Zephyrus cwbrown ryanraaum R.E.A.D EisenLab
  • Toward simpler and faster genome-wide mutagenesis in mice
    Nature Genetics, Vol. 39, No. 7. (17 June 2007), pp. 922-930.
    by Sen Wu, Guoxin Ying, Qiang Wu, Mario R Capecchi
    posted to genome-wide mutation by zwang on 2007-08-28 03:54:37 as * along with 1 person zyfoo
  • Prediction of phenotype and gene expression for combinations of mutations
    Mol Syst Biol, Vol. 3 (27 March 2007)
    by Gregory W Carter, Susanne Prinz, Christine Neou, Patrick J Shelby, Bruz Marzolf, Vesteinn Thorsson, Timothy Galitski
    posted to geneexpression mutation network phenotype by zwang on 2007-03-30 03:55:36 as *** along with 5 people balabu nicoleq gwcarter jo_davies tmmurali
  • Efficient Algorithms for Probing the RNA Mutation Landscape
    PLoS Comput Biol, Vol. 4, No. 8. (2008), e1000124.
    by Jérôme Waldispühl, Srinivas Devadas, Bonnie Berger, Peter Clote
    posted to mutation rna secondary structure by zwang on 2008-08-30 03:59:05 as **
  • Plasmid-chromosome shuffling for non-deletion alleles in yeast
    Nature Methods, Vol. 5, No. 2. (13 January 2008), pp. 167-169.
    by Zhiwei Huang, Richard S Sucgang, Yu-Yi Lin, Xiaomin Shi, Jef D Boeke, Xuewen Pan
    posted to gene mutation yeast by zwang on 2008-07-01 08:38:15 as *** along with 1 person csaveanu
  • Genome instability: a mechanistic view of its causes and consequences.
    Nat Rev Genet (29 January 2008)
    by Andrés Aguilera, Belén Gómez-González
    posted to genome mutation sequence by zwang on 2008-02-19 01:22:05 as ** along with 3 people catcremona inesdesantiago misonneh
  • Single-nucleotide mutation rate increases close to insertions/deletions in eukaryotes
    Nature (20 July 2008)
    by Dacheng Tian, Qiang Wang, Pengfei Zhang, Hitoshi Araki, Sihai Yang, Martin Kreitman, Thomas Nagylaki, Richard Hudson, Joy Bergelson, Jian-Qun Chen
    posted to mutation evolution eukaryota by zwang on 2008-09-06 05:48:52 as ** along with 7 people and 1 group aprasad dakelley psique djkt caseybrown bpcusack gjuggler parkinson's disease references
  • Expanded Tropism and Altered Activation of a Retroviral Glycoprotein Resistant to an Entry Inhibitor Peptide
    J. Virol., Vol. 80, No. 1. (1 January 2006), pp. 353-359.
    by Sean M Amberg, Robert C Netter, Graham Simmons, Paul Bates
    posted to entry mutation tropism virus by zukeboy on 2005-12-13 05:27:25 as **
  • BRCA1 mutations in Algerian breast cancer patients: high frequency in young, sporadic cases.
    International journal of medical sciences, Vol. 5, No. 4. (2008), pp. 197-202.
    by N Uhrhammer, A Abdelouahab, L Lafarge, V Feillel, A Ben Dib, YJ Bignon
    posted to sporadic mutation genetics cancer breast brca algeria africa by Zephyrus on 2008-11-24 14:39:39 as **
  • Mutator pathways unleashed by epigenetic silencing in human cancer.
    Mutagenesis, Vol. 22, No. 4. (July 2007), pp. 247-253.
    by FV Jacinto, M Esteller
    posted to breast cancer epigenetics mutation by Zephyrus on 2008-07-17 00:44:02 as ** along with 1 person srp33
  • Genome-Wide Functional Synergy between Amplified and Mutated Genes in Human Breast Cancer
    Cancer Res, Vol. 68, No. 22. (15 November 2008), pp. 9532-9540.
    by Yuri Nikolsky, Evgeny Sviridov, Jun Yao, Damir Dosymbekov, Vadim Ustyansky, Valery Kaznacheev, Zoltan Dezso, Laura Mulvey, Laura E Macconaill, Wendy Winckler, Tatiana Serebryiskaya, Tatiana Nikolskaya, Kornelia Polyak
    posted to regulation mutation gwas genetics cancer breast amplification by Zephyrus on 2008-12-07 17:50:20 as ** along with 1 person and 1 group chrisamiller Breast Cancer Reading Club
  • Assessing the Evolutionary Impact of Amino Acid Mutations in the Human Genome
    PLoS Genet, Vol. 4, No. 5. (30 May 2008), e1000083.
    by Adam R Boyko, Scott H Williamson, Amit R Indap, Jeremiah D Degenhardt, Ryan D Hernandez, Kirk E Lohmueller, Mark D Adams, Steffen Schmidt, John J Sninsky, Shamil R Sunyaev, Thomas J White, Rasmus Nielsen, Andrew G Clark, Carlos D Bustamante
    posted to read protein mutation genome evolution epidemiology amino-acid by Zephyrus on 2008-11-09 18:35:40 as ** along with 3 people and 1 group madreach bpcusack aprasad R.E.A.D
  • Evolution of a New Function by Degenerative Mutation in Cephalochordate Steroid Receptors
    PLoS Genet, Vol. 4, No. 9. (2008), e1000191.
    by Jamie T Bridgham, Justine E Brown, Adriana Rodríguez-Marí, Julian M Catchen, Joseph W Thornton
    posted to steroid receptor mutation evolution by Zephyrus on 2008-10-30 15:29:08 as ** along with 1 person orr
  • The effects of deleterious mutations on evolution in non-recombining genomes.
    Trends in genetics : TIG (21 November 2008)
    by Vera B B Kaiser, Brian Charlesworth
    posted to read mutation genetics evolution by Zephyrus on 2008-12-05 20:27:29 as ** along with 1 group R.E.A.D
  • The evolution of targeted biologic therapies
    The Breast, Vol. 16 (2007), pp. 1-3.
    by G Sledgejr
    posted to evolepi genomics therapy mutation interesting genetics evolution darwin cancer breast by Zephyrus on 2008-10-30 13:06:48 as ** along with 1 group Breast Cancer Reading Club
  • The EDGE hypothesis: Epigenetically directed genetic errors in repeat-containing proteins (RCPs) involved in evolution, neuroendocrine signaling, and cancer
    Frontiers in Neuroendocrinology, Vol. 29, No. 3. (June 2008), pp. 428-444.
    by D Ruden, D Jamison, B Zeeberg, M Garfinkel, J Weinstein, P Rasouli, X Lu
    posted to evolepi read protein mutation methylation hormone evolution epigenetics endocrine disruption by Zephyrus on 2008-11-07 03:26:05 as ** along with 2 groups R.E.A.D References
  • Mutation as an origin of genetic variability in Helicobacter pylori
    Trends in Microbiology, Vol. 7, No. 12. (1 December 1999), pp. 488-493.
    by Ge Wang, Zafri M Humayun, Diane E Taylor
    posted to mutation pylori variability by xingxu on 2007-12-03 20:43:50 as **
  • High-throughput oncogene mutation profiling in human cancer
    Nature Genetics, Vol. 39, No. 3. (11 February 2007), pp. 347-351.
    by Roman K Thomas, Alissa C Baker, Ralph M Debiasi, Wendy Winckler, Thomas Laframboise, William M Lin, Meng Wang, Whei Feng, Thomas Zander, Laura E Macconnaill, Jeffrey C Lee, Rick Nicoletti, Charlie Hatton, Mary Goyette, Luc Girard, Kuntal Majmudar, Liuda Ziaugra, Kwok-Kin Wong, Stacey Gabriel, Rameen Beroukhim, Michael Peyton, Jordi Barretina, Amit Dutt, Caroline Emery, Heidi Greulich, Kinjal Shah, Hidefumi Sasaki, Adi Gazdar, John Minna, Scott A Armstrong, Ingo K Mellinghoff, Stephen F Hodi, Glenn Dranoff, Paul S Mischel, Tim F Cloughesy, Stan F Nelson, Linda M Liau, Kirsten Mertz, Mark A Rubin, Holger Moch, Massimo Loda, William Catalona, Jonathan Fletcher, Sabina Signoretti, Frederic Kaye, Kenneth C Anderson, George D Demetri, Reinhard Dummer, Stephan Wagner, Meenhard Herlyn, William R Sellers, Matthew Meyerson, Levi A Garraway
    posted to genomics mutation sequencing by xingxu on 2007-08-17 16:51:32 as ** along with 6 people and 1 group huiminC oelemento jfr aviad_work ealloza cerami BioinfoCIPF
  • Novel mutants of the human beta1-adrenergic receptor reveal amino acids relevant for receptor activation.
    J Biol Chem, Vol. 281, No. 26. (30 June 2006), pp. 18120-18125.
    by B Behr, C Hoffmann, G Ottolina, KN Klotz
    posted to activation agonist b2ar binding drug ligands modeling mutation pharmacology structure by xdeupi on 2006-09-05 11:05:20 as *** along with 1 group LabCompMed
  • Mutational and bioinformatics analysis of proline- and glycine-rich motifs in vesicular acetylcholine transporter
    Journal of Neurochemistry, Vol. 98, No. 5. (September 2006), pp. 1551-1559.
    by Chandrasekaran, Ananda, Ojeda, M Ana, Kolmakova, G Natalia, Parsons, M Stanley
    posted to activation channel gly helix mutation pro-kink structure transmembrane by xdeupi on 2006-09-05 11:43:55 as ** along with 1 group LabCompMed
  • A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases
    The EMBO Journal, Vol. aop, No. current. (14 September 2006)
    by Silke Wiesner, Leanne E Wybenga-Groot, Neil Warner, Hong Lin, Tony Pawson, Julie D Forman-Kay, Frank Sicheri
    posted to activation crystallography dynamics mutation nmr switch by xdeupi on 2006-11-17 20:55:01 as ** along with 1 group LabCompMed
  • A conserved carboxylic acid group mediates light-dependent proton uptake and signaling by rhodopsin.
    J Biol Chem, Vol. 269, No. 39. (30 September 1994), pp. 23879-23881.
    by S Arnis, K Fahmy, KP Hofmann, TP Sakmar
    posted to activation dry gpcr ionic lock mutation protonation rhodopsin tm3 by xdeupi on 2006-05-31 15:55:30 as ** along with 1 group LabCompMed
  • Missense mutations in transmembrane domains of proteins: phenotypic propensity of polar residues for human disease.
    Proteins, Vol. 54, No. 4. (1 March 2004), pp. 648-656.
    by AW Partridge, AG Therien, CM Deber
    posted to disease mutation ser transmembrane by xdeupi on 2006-01-27 14:31:44 as ** along with 1 group LabCompMed
  • Comparison of stability predictions and simulated unfolding of rhodopsin structures.
    Photochem Photobiol, Vol. 83, No. 2. (r 2007), pp. 351-363.
    by O Tastan, E Yu, M Ganapathiraju, A Aref, AJ Rader, J Klein-Seetharaman
    posted to folding helix membrane_proteins mutation rhodopsin structure transmembrane by xdeupi on 2007-06-25 10:08:49 as ** along with 1 group LabCompMed
  • The role of proline residues in the dynamics of transmembrane helices: the case of bacteriorhodopsin
    Molecular Membrane Biology, Vol. 23, No. 2. (8211), pp. 127-135.
    by Peralvarez-Marin, Alex, Bourdelande, Jose-Luis, Querol, Enric, Padros, Esteve
    posted to pro-kink structure activation crystallography helix mutation by xdeupi on 2006-09-05 09:47:32 as ** along with 1 group LabCompMed
  • notes Real-time optical recording of beta1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol.
    J Clin Invest, Vol. 117, No. 1. (January 2007), pp. 229-235.
    by F Rochais, JP Vilardaga, VO Nikolaev, M Bünemann, MJ Lohse, S Engelhardt
    posted to activation agonist b2ar helix8 mutation by xdeupi on 2007-03-12 14:39:00 as ***** along with 1 group LabCompMed
  • Multiple residues in the second extracellular loop are critical for M3 muscarinic acetylcholine receptor activation.
    J Biol Chem, Vol. 282, No. 10. (9 March 2007), pp. 7385-7396.
    by M Scarselli, B Li, SK Kim, J Wess
    posted to activation amine binding ecl2 loops mutation by xdeupi on 2007-04-23 10:28:29 as **** along with 1 person and 1 group IrinaMoreira LabCompMed
  • The evolution of transmembrane helix kinks and the structural diversity of G protein-coupled receptors.
    Proc Natl Acad Sci U S A, Vol. 101, No. 4. (27 January 2004), pp. 959-963.
    by S Yohannan, S Faham, D Yang, JP Whitelegge, JU Bowie
    posted to transmembrane structure sequence pro-kink mutation lmc_101 helix evolution by xdeupi on 2006-05-15 15:16:00 as ** along with 1 person and 1 group thaliana LabCompMed
  • Computational Models of Innovative and Creative Design Processes
    Technological Forecasting and Social Change, Vol. 64, No. 2-3. (1 June 2000), pp. 183-196.
    by John S Gero
    posted to creativity design mutation representation routine by willbyrne on 2006-06-15 16:46:50 as *** along with 1 person and 1 group sdipaola HCI-Bham
  • Computational models of creative design processes
    (1994)
    by J Gero
    posted to analogy combination creativity emergence first mutation principles by willbyrne on 2006-06-20 13:43:45 as read along with 1 person and 1 group sdipaola HCI-Bham
  • Crystalline Retinopathies
    Survey of Ophthalmology, Vol. 51, No. 6. ( 2006), pp. 535-549.
    by Kimberly Drenser, David Sarraf, Atul Jain, Kent W Small
    posted to vision review pigments mutation by vahmurk on 2008-09-17 21:55:45 as **
  • Retinitis pigmentosa associated with rhodopsin mutations: Correlation between phenotypic variability and molecular effects
    Vision Research, Vol. 46, No. 27. (December 2006), pp. 4556-4567.
    by Alessandro Iannaccone, David Man, Naushin Waseem, Barbara J Jennings, Madhavi Ganapathiraju, Kevin Gallaher, Elisheva Reese, Shomi S Bhattacharya, Judith Klein-Seetharaman
    posted to rhodopsin pigments photoisomeration mutation membrane md gpcr by vahmurk on 2008-09-17 21:13:30 as **
  • The surface potential on the purple membrane measured using a modified bacteriorhodopsin chromophore as the spectroscopic probe
    FEBS Letters, Vol. 250, No. 2. (3 July 1989), pp. 179-182.
    by B Ehrenberg
    posted to structure spectrum retinal mutation bacteriorhodopsin by vahmurk on 2008-10-07 13:21:16 as **
  • Replacement effects of neutral amino acid residues of different molecular volumes in the retinal binding cavity of bacteriorhodopsin on the dynamics of its primary process.
    Biophys. J., Vol. 70, No. 6. (1 June 1996), pp. 2875-2881.
    by SL Logunov, MA El-Sayed, JK Lanyi
    posted to spectrum photoisomeration photocycle mutation bacteriorhodopsin 081006 by vahmurk on 2008-10-06 09:55:18 as **
  • Theoretical analysis of mutation hotspots and their DNA sequence context specificity
    Mutation Research/Reviews in Mutation Research, Vol. 544, No. 1. (September 2003), pp. 65-85.
    by Igor B Rogozin, Youri I Pavlov
    posted to dna_damage mutation mutation_hotspot review sequence_context by uz_labu_laimi on 2007-03-29 22:09:43 as **
  • Mitochondrial DNA damage and the aging process: facts and imaginations.
    Free Radic Res, Vol. 40, No. 12. (December 2006), pp. 1284-1294.
    by RJ Wiesner, G Zsurka, WS Kunz
    posted to aging deletion dna_damage mtdna mutation reactive_oxygen_species by uz_labu_laimi on 2007-04-12 16:19:36 as **
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